Benzenaminium, N-ethyl-3-hydroxy-N,N-dimethyl-, chloride (1:1)

Edrophonium chloride is the chloride salt of edrophonium. A reversible inhibitor of cholinesterase with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes), it is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals. It has a role as a diagnostic agent, an EC 3.1.1.8 (cholinesterase) inhibitor and an antidote. It is a chloride salt and a quaternary ammonium salt. It contains an edrophonium.

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